welcome to oneFAPvoice
- a positively charged Familial Adenomatous Polyposis community.- join today!
- login
Discovery of a Novel Wnt Inhibitor with Potential to Eradicate Colorectal Cancer Stem Cells
A team including the National Cancer Center (NCC), the RIKEN Center for Life Science Technologies (CLST), and Carna Biosciences Inc. has jointly announced the development of a novel small-molecule Wnt inhibitor named NCB-0846. Wnt signaling is a key pathway of cancer stem cell (CSC) development. The inhibitor may provide a new therapy option for patients with drug-refractory colorectal cancer.

expertly curated content related to this topic
-
Colorectal Cancers Choosing SidesIn contrast to the majority of sporadic ...
-
Medscape Overview on Familial Adenomatous PolyposisFamilial adenomatous polyposis (FAP) is ...
-
Disease Severity and Genetic Pathways in Attenuated Familial Adenomatous Polyposis vary Greatly but Depend on the Si...BACKGROUND: Attenuated familial adenoma...
-
MutY, E. Coli, Homolog of; MUTYHA summary of mutY/MYH/MUTYH...
-
How MicroRNAs Influence Both Hereditary and Inflammatory-Mediated Colon CancersMicroRNAs have emerged as important post...
-
Desmoid Tumors: Clinical Features and Treatment Options for Advanced DiseaseDesmoid tumors describe a rare monoclona...
-
Immunopurification of Adenomatous Polyposis Coli (APC) ProteinsBACKGROUND : The adenomatous polyposis c...