welcome to oneFAPvoice
- a positively charged Familial Adenomatous Polyposis community.- join today!
- login
Mayo Clinic Researcher Finds Potential Target to Control Rare Genetic Disease That Strikes in Teen Years
A new study from researchers at Mayo Clinic Center for Individualized Medicine, described in the New England Journal of Medicine, reveals patients with the most severe FAP disease may benefit from a novel combination therapy. The study points to a possible target for intervention and prevention.
Author Niloy Jewel (Jewel) Samadder, M.D., a gastroenterologist and cancer genetics expert at Mayo Clinic’s campus in Ariz., and his colleagues, studied 171 patients with FAP who had various disease stages, at 20 centers in the U.S., Canada and Europe. Researchers evaluated the benefit and safety of the combination of eflornithine and sulindac compared to each drug alone. The investigation represents the largest international phase III FAP trial to date involving pharmaco-prevention — the use of a medication to prevent the need for surgery or other disease progression.

expertly curated content related to this topic
-
Guide to Fighting Colon Polyps: How to Prevent Colon Polyps Naturally With FoodFrom garlic and turmeric to foods that c...
-
Fate of the Rectal Stump After Colectomy and Ileorectal Anastomosis for Familial Adenomatous PolyposisThe justification of colectomy and ileor...
-
Desmoid Tumors — Dangerous when not Treated as Cancerhttps://www.youtube.com/watch?v=gPcEJ8kA...
-
Familial Colon Cancer Syndromes: An Update of a Rapidly Evolving FieldColorectal cancer (CRC) is a major cause...
-
Surgical Treatment of Familial Adenomatous Polyposis with an Open Technique. Experience of a Third Level Latin Ameri...INTRODUCTION : The ileal pouch-anal anas...
-
Precancerous Colorectal Lesions (Review)Colorectal cancer (CRC) is a common and ...
-
Ileal Pouch-Anal Anastomosis Surgery: Anatomy, Postoperative Complications, and Image-Guided InterventionTotal proctocolectomy with ileal pouch-a...