welcome to oneFAPvoice
- a positively charged Familial Adenomatous Polyposis community.- join today!
- login
Study provides better understanding of sequence of genetic events in colorectal cancer premalignancy
Whole-exome sequencing of both colorectal adenomas (precancers often called polyps) and intestinal mucosa at risk for developing into adenomas from patients with familial adenomatous polyposis (FAP) has generated a comprehensive picture of the genomic alterations that characterize the evolution of normal mucosa to precancer.
expertly curated content related to this topic
-
Colon Polyps and the Prevention of Colorectal CancerThis book explains colon polyps and thei...
-
An APC:WNT Counter-Current-Like Mechanism Regulates Cell Division along the Human Colonic Crypt Axis: A Mechanism th...APC normally down-regulates WNT signalin...
-
More Than Two Decades of APC Modeling in RodentsMutation of tumor suppressor gene adenom...
-
Genetic Predisposition to Colorectal Cancer: Where we Stand and Future PerspectivesThe development of colorectal cancer (CR...
-
Familial and Hereditary Colon Cancerhttp://s3.gi.org/wp-content/uploads/2013...
-
Molecular Targeting of 15-Lipoxygenase-1 (15-LOX-1) for Apoptosis Induction in Human Colorectal CancersPrimary Objective: - To determine whethe...
-
Andalusian Registry for Familial Adenomatous Polyposis. Analysis of Patients IncludedOBJECTIVE : To evaluate the phenotype an...