welcome to oneFAPvoice
- a positively charged Familial Adenomatous Polyposis community.- join today!
- login
Study provides better understanding of sequence of genetic events in colorectal cancer premalignancy
Whole-exome sequencing of both colorectal adenomas (precancers often called polyps) and intestinal mucosa at risk for developing into adenomas from patients with familial adenomatous polyposis (FAP) has generated a comprehensive picture of the genomic alterations that characterize the evolution of normal mucosa to precancer.

expertly curated content related to this topic
-
Distinct Spectrum of APC Germline Mutations in a Familial Adenomatous Polyposis Population from the South of Portuga...Oral Communication Familial adenomato...
-
How to Manage a Patient with Multiple Adenomatous Polyps: History and Clinical Features, Genetic Testing, Surveillan...Adenomatous polyps are found on screenin...
-
Mutation Analysis of the APC Gene in Unrelated Korean Patients with FAP: Four Novel Mutations with Unusual PhenotypeGermline mutations within the adenomatou...
-
The Wnt/Beta-Catenin Pathway and Familial Adenomatous Polyposis Part 1https://www.youtube.com/watch?v=I50ErVv8...
-
MUTYH-Associated Polyposis – Variability of the Clinical Phenotype in Patients with Biallelic and Monoallelic ...To further characterize 215 APC mutation...
-
Genetics, Inheritance and Strategies for Prevention in Populations at High Risk of Colorectal Cancer (CRC)Hereditary forms of colorectal cancer ac...
-
Pathways of Colorectal CarcinogenesisThis review of the molecular and cellula...