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Study uncovers early genetic changes in premalignant colorectal tissue
Researchers at The University of Texas MD Anderson Cancer Center have discovered mutations that may fuel early cancer growth in precancerous colorectal tissue from high-risk patients. Their study, published in Cancer Prevention Research, is the first to use advanced genetic sequencing techniques to characterize genetic changes in precancerous polyps and nearby tissue that has not yet transformed into polyps. In addition to mutations at very early stages of cancer development, the findings identify potential drug targets for colorectal cancer (CRC) prevention.
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