welcome to oneFAPvoice- a positively charged Familial Adenomatous Polyposis community.
- join today!
Prevalence of Small Bowel Polyps in Patients With Sporadic Duodenal Adenomas
study id #: NCT02470416
status: active, not recruitingpurpose:
Little is known about the prevalence of small bowel polyps in patients with sporadic Duodenal/Ampullary polyps. The investigators aim to investigate the prevalence of small bowel polyps in patients with sporadic (ie not related to FAP or PJS) duodenal/ampullary adenomas by performing small bowel capsule endoscopy and comparing the results to those acquired from a control cohort undergoing VCE for accepted indication at our centre.
intervention: Small bowel video capsule endoscopy (VCE) GIVEN/COVIDIEN LTD
start date: October 2015
estimated completion: July 2018
last updated: July 4, 2019
phase of development: Not Available
size / enrollment: 177
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Diagnostic
Investigation for suspected SB tumors is an acceptable indication for VCE. SB polyps occur frequently in patients with FAP/PJS and in patients with FAP, they are significantly more common in patients with Duodenal/Ampullary polyps. Little is known about the prevalence of small bowel polyps in patients with sporadic Duodenal/Ampullary polyps.
The primary hypothesis is that patients with sporadic (ie not related to FAP or PJS) duodenal/ampullary adenomas have a higher prevalence of small bowel polyps compared with patients undergoing VCE for various indications who have not had a duodenal polyp diagnosed or removed.
Patients who have had a previous diagnosis and/or treatment of a duodenal/ampullary polyp at Westmead hospital will receive VCE examination. Control population will consist of age matched controls having VCE for OGIB/IDA at Westmead hospital. Patients will be required to have had a documented colonoscopy within the previous three years. If colonoscopy was not performed within this time frame, the patient will have a colonoscopy as part of the study protocol.
- Number of participants with sporadic (ie not related to FAP or PJS) duodenal/ampullary adenomas [Time Frame:24 months]
- Number of participants with presence and prevalence of colonic polyps [Time Frame:24 months]
• Cases - Patients who were diagnosed with or underwent resection of a duodenal adenoma/ampulloma at Westmead hospital between the years 2005-2014.
• Controls - Patients undergoing VCE procedure for the evaluation of obscure gastrointestinal bleeding (OGIB) or Iron deficiency anemia (IDA).
expertly curated content related to this topic
Genetic testing for hereditary cancer syndromesGenetic testing looks for specific inher...
Thyroid Cancer and Benign Thyroid Disease in Patients with Familial Adenomatous Polyposis (FAP): Memorial Sloan-Kett...Poster Presentation Background: Pati...
Dysplastic Changes in Gastric Fundic Gland Polyps of Patients with Familial Adenomatous PolyposisBACKGROUND : Fundic gland polyps are the...
Coxib-inhibition of Duodenal Polyp Growth in FAPPreliminary data indicate a protective e...
Bonnies Diary Oct 07https://jtvcancersupport.com/embed/26553...
Bioabsorbable Staple Line Reinforcement in Colorectal,Coloanal and Ileoanal AnastomosesThe primary purpose of this prospective,...