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Celecoxib With or Without Eflornithine in Preventing Colorectal Cancer in Patients With Familial Adenomatous Polyposis

key information

study id #: NCT00033371

condition: Colorectal Cancer, Familial Adenomatous Polyposis

status: completed


This randomized phase II trial studies how well giving celecoxib with or without eflornithine works in preventing colorectal cancer in patients with familial adenomatous polyposis. Chemoprevention is the use of certain drugs to keep cancer from forming. The use of celecoxib and eflornithine may keep cancer from forming in patients with familial adenomatous polyposis.

Drug: Celecoxib
Other: Placebo
Drug: eflornithine
Other: Laboratory biomarker analysis
Other: Questionnaire administration

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