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Coxib-inhibition of Duodenal Polyp Growth in FAP
study id #: NCT00844727
condition: Duodenal Polyposis
Preliminary data indicate a protective effect on the development of duodenal polyps by coxib treatment. The hypothesis of the present study is that normal therapy doses of rofecoxib for 1 year would stop or reverse the development of premalignant adenomatous lesions in the duodenal mucosa of FAP patients.
start date: September 2003
estimated completion: April 2004
last updated: July 3, 2011
phase of development: Phase 2, Phase 3
size / enrollment: 38
Intervention Model: Parallel Assignment
Primary Purpose: Treatment
- FAP patient with previous colectomy and confirmed polyposis
- NSAID hypersensitivity
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