French Digestive Polyposis Cohorte | oneFAPvoice

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French Digestive Polyposis Cohorte

study id #: NCT01987518

condition: Quality of Life

status: recruiting


French cohorte about polyposis digestive diseases

Other: Procedure surgery behavioral and genetic diagnosis
Procedure: quality of life after different type of surgery

start date: January 2011

estimated completion: August 2020

last updated: February 28, 2018

size / enrollment: 350

study design:
Observational Model: Cohort
Time Perspective: Retrospective

study description:
Family Adenomatous Polyposis APC and MYH Genes Peutz Jeghers Disease Cowden Disease Festooned polyposis Juvenile polyposis Hyperplastic polyposis

primary outcomes:

  • genetic diagnosis or over 50 polyps in the stomach in the duodenum or in the colon [ Time Frame: 10 years ] [ Designated as safety issue: Yes ]

inclusion criteria:
APC Gene mutation
MYH Homozygote mutation
COWDEN Disease with PTEN gene mutation
Peutz Jeghers Disease with STK 11 gene mutation
Juvenile polyposis with SMAD 4 gene mutation

exclusion criteria:
heterozygote MYH Gene Mutation

sponsor: Hôpital Edouard Herriot

Saurin Jean Christophe, msd
Vinet Olivier, CRA

investigators: Jean Christophe Saurin, MSD

locations: France