Celebrex Reduces Polyps Density in Familial Adenomatous Polyposis (FAP)

This week in the Orphanet Journal of Rare Diseases, an interesting clinical trial was published. Interesting for three reasons. First, it confirmed an earlier study showing a very common drug (Celebrex) may help patients with a rare disease.  Second, it may provide further insight into the pathophysiology of colon cancer developing in patients with familial adenomatous polyposis (FAP). And third, it was a clinical trial in which the intended treatment combination failed to improve outcomes.