Congenital Hypertrophy Retinal Pigment Epithelium as a Manifestation of Colon Cancer | oneFAPvoice

welcome to oneFAPvoice

- a positively charged Familial Adenomatous Polyposis community.
  • join today!
scientific articles

Congenital Hypertrophy Retinal Pigment Epithelium as a Manifestation of Colon Cancer

key information

source: The American Journal of Gastroenterology

year: 2010

authors: Islam S, Islam E, Attaya H, Parupudi S, Shami M, Gonzalez MF, Wachtel M, Nugent K


Congenital hypertrophy retinal pigment epithelium (CHRPE) is a benign lesion of the optic fundus, which typically has no clinical signifi cance. However, the recent development of CHRPE is oft en associated with familial adenomatous polyposis (FAP). Th ere are no reports of its association with a solitary colonic neoplasm. To our knowledge, we present the fi rst case of new CHRPE-like lesions as a presenta-tion of a solitary colonic pre-neoplasm. A 73-year-old woman with cataracts presented to a retina specialist for a routine eye examination. Her history consisted of surgically corrected cataracts in her left eye. She now complained of decreased vision in right eye, which had gotten progressively worse during the past 10 months, aff ecting both her near and distant vision. She con-tinued to have chronic diminished vision in her left eye. Fundoscopy revealed new, multiple lesions found in both eyes, similar to classic CHRPE lesions. Her previous fundoscopic examination 1-year earlier did not show any lesions.

DOI: 10.1038/ajg.2010.256

read more

To improve your experience on this site, we use cookies. This includes cookies essential for the basic functioning of our website, cookies for analytics purposes, and cookies enabling us to personalize site content. By clicking on 'Accept' or any content on this site, you agree that cookies can be placed. You may adjust your browser's cookie settings to suit your preferences.
More information

The cookie settings on this website are set to "allow cookies" to give you the best browsing experience possible. If you continue to use this website without changing your cookie settings or you click "Accept" below then you are consenting to this.