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Celecoxib in a 12-Year-Old Boy with Familial Adenomatous Polyposis
source: International journal of clinical pharmacology and therapeutics
authors: Pérez-Segura P, Bodas A, Sereno M, Martínez-Amores B, Olivera H, Díaz S, López-Asenjo J A, Puente J, Maluenda C, Díaz-Rubio Esummary/abstract:
Familial Adenomatous Polyposis (FAP) is an autosomal dominant disorder characterized by colonic polyps in early adult life. Children with this disease are at risk for colonic cancer, so prophylactic colectomy is the standard treatment to prevent this complication. Chemoprevention experience with NSAIDs in children is exceptional. This case report describes our experience with Celecoxib, a COX-2 inhibitor, in a 12-year-old boy.organization: Hospital Clínico San Carlos
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