welcome to oneFAPvoice
- a positively charged Familial Adenomatous Polyposis community.- join today!
- login
Desmoid Tumours: Our Experience of Six Cases and Review of Literature
source: Journal of clinical and diagnostic research
year: 2014
authors: Kallam A R, Ramakrishna B V, Roy G K, Karthik K R
summary/abstract:Desmoid tumours represent aggressive fibroblastic proliferation of the musculoaponeurotic structures commonly from the anterior abdominal wall. These tumours infiltrate locally, recur frequently but do not metastasize. Antecedent trauma, pregnancy and estrogens play a role in the etiopathogenesis of these tumours. In familial adenomatous polyposis (FAP) genetic history associated with chromosomal abnormality and familial incidence as in Gardner’s syndrome is reported and most of these tumours are intraperitoneal either in the mesentery or pelvis and may be multiple and they carry poor prognosis. Surgery is the most preferred treatment and requires wide excision with 1 cm margin followed by reconstruction of the defect in the anterior abdominal wall either with local musculoaponeurotic layers or with synthetic mesh. In intra-abdominal cases associated with FAP in addition to surgery, hormonal treatment, chemotherapy and Radiotherapy are also advised depending upon the particular condition but usually prognosis is not encouraging. In this article we present our personal experience in the successful treatment of six cases of sporadic desmoids, five in females of child bearing age, and all in the anterior abdominal wall and one extra abdominal in a child aged 13 y in the gluteal region (Case 6). It is very interesting and unique to see two desmoid tumours developing in the same patient (Case2)one in each of the Rectus abdominal muscles (Right & Left).
organization: Alluri Sitarama Raju Institute of Medical SciencesDOI: 10.7860/JCDR/2014/9610.5032
read more
expertly curated content related to this topic
-
Desmoid Tumour in Familial Adenomatous Polyposis Patients: Responses to TreatmentsNo guidelines for desmoid tumors (DT) ma...
-
Familial Adenomatous PolyposisFamilial adenomatous polyposis (FAP) is ...
-
Inherited Cancer Syndromes: Current Clinical ManagementElectronic Book: The second edition of I...
-
Early Onset of Dysplasia in Polyps in Children with Familial Adenomatous Polyposis: Case Report and Literature Revie...Familial adenomatous polyposis (FAP) is ...
-
The Proper Diagnostic Pathway of Gardner’s Syndrome: Role of the Dentist in the Early Detection of the Associated ...Gardner’s syndrome is a genetic diseas...
-
Mow down Gardner SyndromeGardner Syndrome (GS) is a rare disease....
-
The Evolution of Colorectal Cancer Genetics-Part 2: Clinical Implications and ApplicationsThe genetic understanding of colorectal ...