welcome to oneFAPvoice
- a positively charged Familial Adenomatous Polyposis community.- join today!
- login
Diagnosis, Surveillance, and Treatment Strategies For Familial Adenomatous Polyposis: Rationale and Update
source: European journal of gastroenterology & hepatology
year: 2014
authors: Aihara H, Kumar N, Thompson C C
summary/abstract:Familial adenomatous polyposis is characterized by the development of multiple (>100) colorectal adenomas throughout the colorectum. This disorder can be caused by a germline mutation in the adenomatous polyposis coli gene and can be diagnosed either clinically or genetically. After diagnosis with the condition, patients should undergo prophylactic proctocolectomy with a neoreservoir, usually an ileoanal pouch, at an appropriate time. Individuals with a family history of this disease who have not been diagnosed should be advised to attend genetic counseling and to enroll in appropriate clinical and genetic surveillance programs. Recent progress in endoscopic technology, including high-resolution endoscopy, capsule endoscopy, and double-balloon endoscopy, has made possible more detailed and wide-ranging investigation of the gastrointestinal tract. Although there has been limited evidence, further studies on these new endoscopic technologies might alter the surveillance strategies for familial adenomatous polyposis.
organization: Brigham and Women's HospitalDOI: 10.1097/MEG.0000000000000010
read more full text source
expertly curated content related to this topic
-
Effect of Sulindac and Erlotinib vs Placebo on Duodenal Neoplasia in Familial Adenomatous Polyposis: A Randomized Cl...IMPORTANCE: Patients with familial aden...
-
Myh-Associated Polyposis (Approved by the Cancer.Net Editorial Board)MYH-associated polyposis (MAP) is a here...
-
Strategy for Surgery in Familial Adenomatous Polyposis Patients with Invasive Colorectal CancerPURPOSE : Total proctocolectomy with ile...
-
Local Ostomy Model Saleem Juma Works to Demystify DisabilitySaleem Juma walks into the disability of...
-
Sulindac Sulfone is Most Effective in Modulating Beta-Catenin-Mediated Transcription in Cells with Mutant APCSulindac sulfone (FGN-1, Aptosyn), a met...
-
BCIR for People with a Malfunctioning Kock Pouch or J-Pouchhttps://www.youtube.com/watch?v=mO2eC7ou...