welcome to oneFAPvoice
- a positively charged Familial Adenomatous Polyposis community.- join today!
- login
Diagnosis, Surveillance, and Treatment Strategies For Familial Adenomatous Polyposis: Rationale and Update
source: European journal of gastroenterology & hepatology
year: 2014
authors: Aihara H, Kumar N, Thompson C C
summary/abstract:Familial adenomatous polyposis is characterized by the development of multiple (>100) colorectal adenomas throughout the colorectum. This disorder can be caused by a germline mutation in the adenomatous polyposis coli gene and can be diagnosed either clinically or genetically. After diagnosis with the condition, patients should undergo prophylactic proctocolectomy with a neoreservoir, usually an ileoanal pouch, at an appropriate time. Individuals with a family history of this disease who have not been diagnosed should be advised to attend genetic counseling and to enroll in appropriate clinical and genetic surveillance programs. Recent progress in endoscopic technology, including high-resolution endoscopy, capsule endoscopy, and double-balloon endoscopy, has made possible more detailed and wide-ranging investigation of the gastrointestinal tract. Although there has been limited evidence, further studies on these new endoscopic technologies might alter the surveillance strategies for familial adenomatous polyposis.
organization: Brigham and Women's HospitalDOI: 10.1097/MEG.0000000000000010
read more full text source
expertly curated content related to this topic
-
Colorectal Cancer: Are Genetic Tests Clinically Useful?More than 1.2 million new cases of color...
-
Medline Plus Overview on Colorectal Polyps: Causes, Symptoms, and ManagementA colorectal polyp is a growth on the li...
-
Berberine Potently Attenuates Intestinal Polyps Growth in ApcMin Mice and Familial Adenomatous Polyposis Patients Th...As a traditional anti-inflammatory Chine...
-
Laparoscopic Colectomy and Restorative Proctocolectomy for Familial Adenomatous PolyposisBACKGROUND : Familial adenomatous polypo...
-
Familial Risk-Colorectal Cancer: ESMO Clinical Practice GuidelinesLynch syndrome is the most common heredi...
-
Colon-Specific Delivery of Celecoxib is a Potential Strategy to Improve Toxicological and Pharmacological Properties...In general, colon-specific delivery of a...
-
Endoscopic Management of Familial Adenomatous Polyposis in Patients Refusing ColectomyBACKGROUND AND STUDY AIMS: Colectomy pr...