welcome to oneFAPvoice- a positively charged Familial Adenomatous Polyposis community.
- join today!
Different Surgical Strategies in the Treatment of Familial Adenomatous Polyposis: What’s the Role of the Ileorectal Anastomosis?
source: Acta Gastro-Enterologica Belgica
authors: Wolthuis AM, Leonard D, Kartheuser A, Bruyninx L, Van De Stadt J, Van Cutsem E, D'Hoore Asummary/abstract:
Prophylactic (procto-) colectomy is the treatment of choice to reduce the risk of colorectal cancer in FAP patients with multiple adenomas. Because patients present at young age, rectum-sparing surgery is sometimes advocated, so that there is no pelvic dissection with impact on quality of life, preserved pelvic innervation and sexual function and fertility. The main disadvantage of a total colectomy with an ileorectal anastomosis (IRA) is a rectal cancer risk of 50% at the age of 50 years and a cumulative risk of 25.8% after 25 years of follow-up. Therefore, this procedure should be reserved for patients with an unaffected rectum. There should be no discussion to perform a primary IPAA in patients with multiple rectal adenomas (> 20) or those with a severe dysplastic or large (> 3 cm) rectal adenoma or a cancer elsewhere in the colon. A patient with an IRA should undergo yearly follow-up by rectoscopy.organization: Belgian Familial Adenomatous Polyposis Association (FAPA)
expertly curated content related to this topic
Surgical Prophylaxis in Familial Adenomatous Polyposis: Do Pre-Existing Desmoids Outside the Abdominal Cavity Matter...Desmoid tumours (DT) are myofibroblastic...
Low-Dose Dacarbazine-Doxorubicin Therapy Against Intra-Abdominal Desmoid TumorsIntra-abdominal desmoid tumor is a life-...
Rectal Epithelial Apoptosis in Familial Adenomatous Polyposis Patients Treated with SulindacBACKGROUND : Sulindac regresses colorect...
The Traveling J-Pouch: More Tips for Going Abroad with a J-Pouchhttps://www.youtube.com/watch?v=Vk5AmBLF...
Our Experience of Treatment of Cribriform Morular Variant of Papillary Thyroid Carcinoma; Difference in Clinicopatho...Cribriform-morular variant (CMV) is a co...
Assessment of Endostatin Gene Therapy for Familial Adenomatous Polyposis-related Desmoid TumorsConstitutive activation of the Wnt signa...
Adenomatous Polyposis Syndromeshttps://www.youtube.com/watch?v=pFn-A2jZ...