welcome to oneFAPvoice
- a positively charged Familial Adenomatous Polyposis community.- join today!
- login
Early Postoperative Complications After Stapled vs Handsewn Restorative Proctocolectomy with Ileal Pouch-Anal Anastomosis in 148 Patients with Familial Adenomatous Polyposis Coli: A Matched-Pair Analysis
source: Colorectal disease
year: 2014
authors: Ganschow P, Warth R, Hinz U, Büchler M W, Kadmon M
summary/abstract:AIM : Restorative proctocolectomy with ileal pouch-anal anastomosis for patients with familial adenomatous polyposis (FAP) and ulcerative colitis (UC) has been modified from a transanal hand-suture after mucosectomy to a stapled ileal pouch-anal anastomosis (IPAA) without mucosectomy. Better functional results favour stapled anastomosis; however, stapled anastomosis results in higher rates of adenomas in persisting anorectal mucosa. The purpose of this study was to compare the two techniques of pouch-anal anastomosis with respect to early postoperative complications in a collective of FAP patients.
METHOD : The study was performed as a matched-pair analysis. Data were obtained from a prospectively collected database.
RESULTS : The overall rate of postoperative complications was higher after stapled IPAA (31% stapled vs 23% handsewn), with anastomotic stricture occurring in 24.3% (stapled) and 16.2% (handsewn) (P = 0.22). Any leakage or pelvic abscess formation after stapled anastomosis occurred within 30 days in almost all patients, whereas these were mainly diagnosed between 30 days and 6 months after handsewn IPAA. A laparoscopic approach was used in 56.7% of patients in the stapled group but in only two patients in the handsewn group. Intra-operative blood loss was significantly higher in the handsewn group (mean ± SD: 699 ± 511 ml vs 369 ± 343 ml; P < 0.0001), as was the volume of blood transfused (mean ± SD: 205 ± 365 ml vs 8 ± 49 ml; P < 0.0001). Function did not differ between the groups.
CONCLUSION : There was a nonstatistically significant tendency towards a higher rate of early postoperative complications after stapled IPAA. The timing of anastomotic leakage and abscess formation differed between the groups.
organization: University of HeidelbergDOI: 10.1111/codi.12385
read more full text source
expertly curated content related to this topic
-
Bonnies Diary Jan 08https://jtvcancersupport.com/embed/29153...
-
Combination Treatment with Curcumin and Quercetin of Adenomas in Familial Adenomatous PolyposisBACKGROUND & AIMS : Familialadenomat...
-
Genetic Polymorphisms of Human Flavin Monooxygenase 3 in Sulindac-Mediated Primary Chemoprevention of Familial Adeno...PURPOSE : Sulindac is a nonsteroidal ant...
-
Good Bye ColonHi there and welcome to Good Bye Colon. ...
-
Registry With Information About Colitis Ulcerosa and Familial Adenomatous Polyposis PatientsThe purpose of this registry is to colle...
-
Non-Surgical Management of Attenuated and Deleterious (Classical) Familial Adenomatous Polyposis: A Long-term Survei...The primary objective of this chart revi...
-
Open Versus Laparoscopic (Assisted) Ileo Pouch Anal Anastomosis for Ulcerative Colitis and Familial Adenomatous Poly...BACKGROUND : Restorative proctocolectomy...