Familial Adenomatous Polyposis and Hypertension | oneFAPvoice

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Familial Adenomatous Polyposis and Hypertension

key information

source: Lancet

year: 2010

authors: Hopkins T G, Salem V, El-Gayar H, Palazzo F F, Meeran K, Tan T


In October, 2008, a 36-year-old man was referred to our unit with new onset of hypertension and adrenal hyperplasia. He had been diagnosed with familial adenomatous polyposis (FAP) in childhood, and had undergone a total colectomy at the age of 17 years. He had been under endoscopic surveillance since, with a recent polyp count of 50–60 (March). The next month, as part of his routine FAP screening programme, he had an abdominal CT scan, which showed bilateral macronodular adrenal hyperplasia. The largest nodule measured 4 cm by 2 cm on the right and 2·7 cm by 2·9 cm on the left (figure).

organization: Imperial College Healthcare NHS Trust

DOI: 10.1016/S0140-6736(10)60405-9

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