Macroscopic and Histologic Regression of Duodenal Polyposis with FOLFOX4 Chemotherapy for an Ileal Pouch Adenocarcinoma in a Patient with Familial Adenomatous Polyposis | oneFAPvoice

welcome to oneFAPvoice

- a positively charged Familial Adenomatous Polyposis community.
  • join today!
scientific articles

Macroscopic and Histologic Regression of Duodenal Polyposis with FOLFOX4 Chemotherapy for an Ileal Pouch Adenocarcinoma in a Patient with Familial Adenomatous Polyposis

key information

source: Endoscopy

year: 2012

authors: Pioche M, Aguero Garcete G, Forestier J, Lépilliez V, Lombard-Bohas C, Saurin J C, Nozières V

summary/abstract:

Severe (stage IV) duodenal polyposis is difficult to manage in patients with familial adenomatous polyposis (FAP), with no effective medical treatment, complex endoscopic treatment modalities, and a high morbidity and mortality from pancreaticoduodenectomy. We present the case of a 44-year-old woman with FAP, stage IV duodenal polyposis, and with an ileal pouch adenocarcinoma that required surgery and adjuvant chemotherapy. Her duodenal polyposis regressed to stage II after four sessions of FOLFOX4 adjuvant chemotherapy, which avoided the need for aggressive endoscopic therapy or pancreatoduodenectomy in this patient.

organization: Edouard Herriot Hospital

DOI: 10.1055/s-0032-1325674

read more full text source

To improve your experience on this site, we use cookies. This includes cookies essential for the basic functioning of our website, cookies for analytics purposes, and cookies enabling us to personalize site content. By clicking on 'Accept' or any content on this site, you agree that cookies can be placed. You may adjust your browser's cookie settings to suit your preferences.
More information

The cookie settings on this website are set to "allow cookies" to give you the best browsing experience possible. If you continue to use this website without changing your cookie settings or you click "Accept" below then you are consenting to this.

Close