welcome to oneFAPvoice
- a positively charged Familial Adenomatous Polyposis community.- join today!
- login
Outcome After Ileal Pouch-Anal Anastomosis for Familial Adenomatous Polyposis Compared to Mucosal Ulcerative Colitis in a Middle Eastern Population
source: Annals of Saudi medicine
year: 2013
authors: Al-Sanea N, Alfaifi J, Homoud S A, Abduljabbar A, Hibbert D, Ashari L
summary/abstract:BACKGROUND AND OBJECTIVES : To compare the complications and outcome after ileal pouch-anal anastomosis (IPAA) for mucosal ulcerative colitis (MUC) and familial adenomatous polyposis (FAP).
DESIGN AND SETTINGS : This is a retrospective study. The study was conducted at a single tertiary referral center.
METHODS : All patients who underwent restorative proctocolectomy with IPAA at a tertiary center in Saudi Arabia from 2001 till 2009 were retrieved. Data was obtained regarding preoperative status, postoperative complications, and functional outcome.
RESULTS : A total of 40 patients underwent IPAA, of which 21 cases were of FAP and 19 cases of MUC. Median age at operation for FAP and MUC was 31 (range: 16-45) and 43 (range: 15-65) years, respectively (P < .05). Median length of stay was 10 days (range: 6-42) for FAP and 12 days (range: 9-27) for MUC (P=.1). Postoperative morbidity was noted in 4 cases of FAP and 6 cases of MUC (P=.36). Specifically, wound infection was noted in 2 cases of FAP compared to 3 cases of MUC (P=.55); 1 MUC case had an anastomotic leak (P=.29). One mortality was recorded among the FAP cases (P=.35). The time between the creation of IPAA and the closure of ileostomy was 4.5 and 5 months for FAP and MUC, respectively (P=.87). Median follow-up was 36 months. Median bowel frequency per 24 hours was 6 (range: 3-24) for FAP and 7 (range 3-17) for MUC (P=.54). Intestinal obstruction was reported in 3 cases of FAP and 5 cases of MUC (P=.38). One pouch was excised in a FAP patient. One case of MUC developed pouchitis.
CONCLUSIONS : The outcome after IPAA was inferior for MUC compared to FAP, but it was not statistically significant due to the small sample size. The morbid status of the MUC cases and their older age contributed to the minor differences.
organization: King Faisal Specialist Hospital and Research CentreDOI: 10.5144/0256-4947.2013.268
read more
expertly curated content related to this topic
-
Colon Cancer Combating Recipes (Main Dishes)Are you looking for inspiring recipes fo...
-
Pouchitis: What Every Gastroenterologist Needs to KnowPouchitis is the most common complicatio...
-
@JJ_HOPE23I'm a 5 x stage IV #coloncancer #survi...
-
Single-Incision Laparoscopic Ileal Pouch-Anal Anastomosis in Children–How Does it Compare to a Laparoscopic-As...BACKGROUND : Although single-incision la...
-
papa’s got a brand new bagThe reason for this page is to give a un...
-
Impact of Familial Adenomatous Polyposis on Young Adults: Attitudes toward Genetic Testing, Support, and Information...PURPOSE: The study assessed views conce...