welcome to oneFAPvoice
- a positively charged Familial Adenomatous Polyposis community.- join today!
- login
Papillary Thyroid Cancer in a Patient with MUTYH-Associated Polyposis (MAP)
source: Familial cancer
year: 2010
authors: Pervaiz M A, Eppolito A, Schmidt K
summary/abstract:We describe a patient with MUTYH-associated polyposis diagnosed with colon cancer at 33 years of age, as well as gastric polyps at a later age. She was also diagnosed with papillary thyroid cancer at age 35. MUTYH-associated polyposis is an autosomal recessively inherited disease which has clinical overlap with Familial adenomatous polyposis and its attenuated form, in that it is associated with risk of colon cancer at a young age. Extra-intestinal cancers have also been reported in patients with MUTYH-associated polyposis; however the tumor spectrum is still evolving. National Comprehensive Cancer Network guidelines recommend screening for colon, duodenal and gastric polyps in individuals with MUTYH-associated polyposis. Screening for extra-intestinal cancers i.e. thyroid cancer is presently not part of these recommendations. These will likely continue to evolve as the MUTYH-associated polyposis tumor spectrum is better understood as a result of future case reports and research.
organization: Emory University School of MedicineDOI: 10.1007/s10689-010-9366-1
read more full text source
expertly curated content related to this topic
-
Could APC Gene Screening be Useful in Children with Hepatoblastoma? Early Onset of Adenocarcinoma in a Child with Fa...Familial adenomatous polyposis is an inh...
-
Screening for Colorectal Cancer: It’s the Right Choicehttps://www.fapvoice.com/wp-content/uplo...
-
For the (Medical) Record: What I Wished My Doctors Knew About Familial Adenomatous PolyposisOver the years, you’ve been judiciousl...
-
Magnified Endoscopic Observation Using Narrow-Band Imaging of Periampullary Adenoma in a Patient with Familial Adeno...BACKGROUND : Adenoma of the major papill...
-
Macroscopic and Histologic Regression of Duodenal Polyposis with FOLFOX4 Chemotherapy for an Ileal Pouch Adenocarcin...Severe (stage IV) duodenal polyposis is ...
-
Surveillance of FAP: A Prospective Blinded Comparison of Capsule Endoscopy and Other GI Imaging to Detect Small Bowe...BACKGROUND : Familial adenomatous polypo...
-
Desmoid Update – NIH clinical trial!https://www.youtube.com/watch?v=OE_GSI8A...