welcome to oneFAPvoice
- a positively charged Familial Adenomatous Polyposis community.- join today!
- login
Pouch-Anal Anastomosis vs Straight Ileoanal Anastomosis in Pediatric Patients: A Meta-Analysis
source: Journal of pediatric surgery
year: 2006
authors: Henry S. Tilney, Vasilis Constantinides, Adonis S. Ioannides, Paris P. Tekkis, Munther J. Haddad, Ara W. Darzi
summary/abstract:BACKGROUND : Restorative proctocolectomy is the treatment of choice for pediatric patients with refractory colitis, inherited polyposis syndromes, and some with colonic aganglionosis. Evidence concerning the optimal method of reconstruction is, however, sparse.
METHODS : Studies comparing outcomes from ileal pouch-anal anastomosis (IPAA) and straight ileoanal anastomosis (SIAA) were identified by searching Medline, Ovid, and Embase. Suitable studies were selected and data extracted for meta-analysis.
RESULTS : Of 13 studies identified by literature search, 5 satisfied the inclusion criteria, comprising a total of 306 patients, 86 of whom (28.1%) underwent SIAA, and the remainder, IPAA. Pouch failure was more common in the SIAA group (odds ratio, 3.21; confidence interval, 1.24-8.34), as were abdominal salvage procedures (odds ratio, 9.5; confidence interval, 3.14-28.77). Short-term adverse events were similar between the 2 groups, with the exception of perianal sepsis, the higher frequency of which, in SIAA, just reached statistical significance. Bowel frequency was lower in the IPAA patients, although few studies presented functional data in a comparable form.
CONCLUSIONS : There are few good-quality studies that compare the outcomes from SIAA and IPAA, meaning that caution should be exercised in the generalization of the results of this meta-analysis, which suggests pouch procedures to be favorable in terms of reconstruction survival and functional outcome.
organization: Imperial College Londonread more full text source
expertly curated content related to this topic
-
diane’s storyI was devastated, I had made all my arra...
-
SCALEing F.A.P.: Impact of J-Pouch Surgeries on My Weighthttps://www.youtube.com/watch?v=Nz2p-KzD...
-
Familial Colon Cancer Syndromes: An Update of a Rapidly Evolving FieldColorectal cancer (CRC) is a major cause...
-
Restorative Proctocolectomy and Ileal Pouch-Anal Anastomosis in ChildrenPURPOSE : This study was designed to eva...
-
APC-Associated Polyposis ConditionsCLINICAL CHARACTERISTICS : APC-associate...
-
Is Diverting Ileostomy Necessary in Stapled Ileoanal Pouch?Total proctocolectomy with ileal pouch a...
-
Female Sexual Function and Fertility After Ileal Pouch-Anal AnastomosisPURPOSE : A potential complication in wo...