welcome to oneFAPvoice
- a positively charged Familial Adenomatous Polyposis community.- join today!
- login
Quality of Life Ten and More Years After Restorative Proctocolectomy for Patients with Familial Adenomatous Polyposis Coli
source: Diseases of the colon and rectum
year: 2010
authors: Ganschow P, Pfeiffer U, Hinz U, Leowardi C, Herfarth C, Kadmon M
summary/abstract:PURPOSE : Few studies on long-term quality of life after restorative proctocolectomy and ileal pouch-anal anastomosis have been published. Most of them survey a mixed patient population of familial adenomatous polyposis and ulcerative colitis. The present study analyzes long-term results more than 10 years after ileal pouch-anal anastomosis for patients with familial adenomatous polyposis, exclusively.
METHODS : One hundred thirty-five patients who underwent ileal pouch-anal anastomosis more than 10 years ago were identified from the prospective familial adenomatous polyposis registry at Heidelberg University hospital. They received the German version of the health-specific Short Form 36 Health Survey and the disease-specific Gastrointestinal Quality of Life Index by mail. To assess the impact of disease-specific factors, 10 questions asking for ability to work, current medication, pouchitis, and extracolonic manifestations of familial adenomatous polyposis were added to the Gastrointestinal Quality of Life Index questionnaire.
RESULTS : Among 84 patients who answered the questionnaires the median follow-up was 13.4 years (range, 10.3-23.8 y).The results of the Short Form 36 Health Survey were comparable to a German normative population in all dimensions, whereas the overall score for the Gastrointestinal Quality of Life Index was significantly reduced compared with healthy individuals (111.8 vs 120.8, P = .0014). Carcinoma at the time of ileal pouch-anal anastomosis, desmoid tumors, or duodenal adenomas had no significant influence on quality of life. More than 7 bowel movements during the daytime were found to reduce quality of life significantly (103.5 vs 115, P = .0127). More than 2 defecations per night diminished the score further (101 vs 125, P < .0001). Patients younger than 40 years at the time of ileal pouch-anal anastomosis had significantly better results than older patients (120 vs 109.5, P = .0076).
CONCLUSION : Ileal pouch-anal anastomosis is a safe surgical procedure with a high quality of life comparable to that of a normative population after long-term follow-up of patients with familial adenomatous polyposis.
organization: University of HeidelbergDOI: 10.1007/DCR.0b013e3181e56feb
read more full text source
expertly curated content related to this topic
-
Functional Outcomes Following Ileal Pouch-Anal Anastomosis (IPAA) in Older Patients: A Systematic ReviewAIM : Ileal pouch-anal anastomosis (IPAA...
-
PTSD common in patients with familial adenomatous polyposisPosttraumatic stress disorder is common ...
-
Charlotte Gallagher ‘On Better Days’https://www.youtube.com/watch?v=7i47h-0b...
-
Practical guide to exocrine pancreatic insufficiency – Breaking the mythsBACKGROUND: Exocrine pancreatic insuf...
-
F.A.P.’s Got Your Tongue: Talking About Longterm Chronic Illnesshttps://www.youtube.com/watch?v=Lp6YCvpk...
-
Celebrating 20 Years Since He Was Diagnosed With Colon Cancer, With Kris ThompsonIt’s been 20 years since Kris Thompson...
-
familial adenomatous polyposis and desmoid tumour support groupFor people with FAP and Desmoids and als...