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Rare Combination of Familial Adenomatous Polyposis and Gallbladder Polyps
source: World Journal of Gastroenterology
authors: Yasuhisa Mori, Norihiro Sato, Nobutaka Matayoshi, Toshihisa Tamura, Noritaka Minagawa, Kazunori Shibao, Aiichiro Higure, Koji Yamaguchisummary/abstract:
Familial adenomatous polyposis is associated with a high incidence of malignancies in the upper gastrointestinal tract (particularly ampullary adenocarcinomas). However, few reports have described a correlation between familial adenomatous polyposis and gallbladder neoplasms. We present a case of a 60-year-old woman with familial adenomatous polyposis who presented with an elevated mass in the neck of the gallbladder (measuring 16 mm × 8 mm in diameter) and multiple small cholecystic polyps. She had undergone a total colectomy for ascending colon cancer associated with familial adenomatous polyposis 22 years previously. The patient underwent laparoscopic cholecystectomy under a preoperative diagnosis of multifocal gallbladder polyps. Pathologic examination of the resected gallbladder revealed more than 70 adenomatous lesions, a feature consistent with adenoma of the gallbladder. This case suggests a requirement for long-term surveillance of the biliary system in addition to the gastrointestinal tract in patients with familial adenomatous polyposis.organization: University of Occupational and Environmental Health, Kitakyushu, Fukuoka, Japan
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