welcome to oneFAPvoice- a positively charged Familial Adenomatous Polyposis community.
- join today!
Regression of Colonic Adenomas After Treatment with Sulindac in Familial Adenomatous Polyposis: A Case with a 2-Year Follow-Up Without a Prophylactic Colectomy
source: Annals of coloproctology
authors: Kim K Y, Jeon S W, Park J G, Yu C H, Jang S Y, Lee J K, Hwang H Ysummary/abstract:
Familial adenomatous polyposis (FAP) is an autosomal dominant disorder characterized by hundreds of colorectal adenomatous polyps that progress to colorectal cancer. Management of patients with FAP is with a total colectomy. Chemopreventive strategies have been studied in FAP patients in an effort to delay the development of adenomas in the upper and the lower gastrointestinal tract and to prevent recurrence of adenomas in the retained rectum of patients after prophylactic surgery. Sulindac, a nonsteroidal anti-inflammatory drug, causes regression of colorectal adenomas in the retained rectal segment of FAP patients. However, evidence regarding long-term use of this therapy and its effect on the intact colon has been insufficient. We report a case in which the long-term use of sulindac was effective in reducing the size and the number of colonic polyps in patients with FAP without a prophylactic colectomy and polypectomy; we also present a review of the literature.organization: Kyungpook National University School of Medicine
read more full text source
expertly curated content related to this topic
Total Proctocolectomy, Ileal Pouch Anal Anastomosis (J-Pouch, S-Pouch, W-Pouch)http://my.clevelandclinic.org/ccf/media/...
Familial Polyposis and Lynch Syndrome Review March 2014http://www.slideshare.net/douglasriegert...
Rectal Epithelial Apoptosis does not Predict Response to Sulindac Treatment or Polyp Development in Presymptomatic F...Innormal colorectal epithelium, apoptosi...
The Effect of Ursodesoxycholic Acid on Duodenal Adenomas in Familial Adenomatous Polyposis: A Prospective Randomized...AIM: Duodenal adenomas occur in about 9...
@hopelovefaith30Laughter, Friendship, Snacks & Tequi...
Long-term Results After Restorative Proctocolectomy With Ileal Pouch-Anal Anastomosis at a Young AgeBACKGROUND: Restorative proctocolectomy...
Jon Olis’s StoryAfter being misdiagnosed with hemorrhoid...