welcome to oneFAPvoice
- a positively charged Familial Adenomatous Polyposis community.- join today!
- login
Risk of Cancer in the Rectal Remnant after Ileorectal Anastomosis in Patients with Familial Adenomatous Polyposis: Single Center Experience
source: Digestive Endoscopy
year: 2015
authors: Maehata Y, Esaki M, Nakamura S, Hirahashi M, Ueki T, Iida M, Kitazono T, Matsumoto T
summary/abstract:BACKGROUND AND AIM:
We aimed to evaluate the long-term risk of cancer in the rectal remnant in patients with familial adenomatous polyposis after ileorectal anastomosis.
METHODS:
Cumulative incidence and clinicopathological characteristics of cancer in the rectal remnant were retrospectively investigated in 27 patients with familial adenomatous polyposis who had undergone ileorectal anastomosis.
RESULTS:
During the follow-up period ranging from 3.0 to 35.0 years (median, 21.1 years), cancer in the rectal remnant developed in 10 patients. Cumulative risk of cancer in the rectal remnant 30 years after surgery was 57%. Five patients had metastases and three patients died of cancer in the rectal remnant after proctectomy. There was a trend towards a higher incidence of cancer in the rectal remnant in patients with small-intestinal adenoma and congenital hypertrophy of the retinal pigment epithelium. Multivariate analysis revealed that the ocular lesion was an independent risk factor associated with cancer in the rectal remnant.
CONCLUSION:
Subtotal colectomy with ileorectal anastomosis does not seem to be an appropriate prophylactic surgery in patients with familial adenomatous polyposis.
organization: Department of Medicine and Clinical Science, Kyushu University, Fukuoka, JapanDOI: 10.1111/den.12414
read more full text source
expertly curated content related to this topic
-
Morbidity of Loop Ileostomy Closure after Restorative Proctocolectomy for Ulcerative Colitis and Familial Adenomatou...BACKGROUND: Temporary loop ileostomy is...
-
Ostomy cleaning and wearhttps://www.youtube.com/watch?v=ZQ3PEnI7...
-
fap & pregnancyHello everybody! So obviously, my quest...
-
Distinct Microbiome in Pouchitis Compared to Healthy Pouches in Ulcerative Colitis and Familial Adenomatous Polyposi...BACKGROUND : Pouchitis occurs in up to 5...
-
#FamilialAdenomatousPolyposisFAP hashtag for the community...
-
@Joann_458I have familial adenomatous polyposis, s...