welcome to oneFAPvoice- a positively charged Familial Adenomatous Polyposis community.
- join today!
Summer’s Complaint: My family’s courageous, century-long struggle with a rare genetic cancer syndrome
Familial Adenomatous Polyposis, or FAP, accounts for roughly 1 percent of hereditary colorectal cancer and carries an extremely high lifetime risk of colon cancer and elevated risks for other exceedingly rare cancers. It is an autosomal dominant condition caused by germline mutations in the adenomatous polyposis coli (APC) gene. By the age of fifty, nearly 99 percent of untreated FAP patients will have developed cancer.
This is the dark shadow that has lingered over one family since at least 1911, when a matriarch was first seen at the Mayo Clinic in Rochester, Minnesota for symptoms that would become commonplace in her descendants. Three of her five children died in their thirties with what they’d come to call “summer’s complaint.” Her granddaughter, genetically programmed by a defect on her 5th chromosome also developed cancer, which would ultimately take her life.
expertly curated content related to this topic
A Life ReconstructedWe got this... This has been the mantra ...
F.A.P.’s Got Your Tongue: Talking About Longterm Chronic Illnesshttps://www.youtube.com/watch?v=Lp6YCvpk...
Three Sisters, One Colonhttps://www.youtube.com/watch?v=JQpt3b-j...
like a pork chop in a synagogue (resilience)I've seen some stuff, I've done some stu...
2018 Rose Parade: colon, thyroid cancer survivor: embracing the ‘new me’Looking at her, you would never guess th...
Familial Adenomatous Polyposis by Sarah-Jane Shawhttps://www.youtube.com/watch?v=XTLe5XC2...